Parhi, Ajit: search on Z-Library

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1

Crystallographic Fragment Screening and Structure-Based Optimization Yields a New Class of Influenza Endonuclease Inhibitors

Bauman, Joseph D., Patel, Disha, Baker, Steven F., Vijayan, R. S. K., Xiang, Amy, Parhi, Ajit K., Martínez-Sobrido, Luis, LaVoie, Edmond J., Das, Kalyan, Arnold, Eddy

Journal:

ACS Chemical Biology

Year:

2013

Language:

english

File:

PDF, 1.49 MB

english, 2013

2

In vivo Pharmacodynamic Evaluation of an FtsZ Inhibitor, TXA-709 and its Active Metabolite TXA-707, in the Murine Neutropenic Thigh Infection Model

Lepak, Alexander J., Parhi, Ajit, Madison, Michaela, Marchillo, Karen, VanHecker, Jamie, Andes, David R.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2015

Language:

english

File:

PDF, 555 KB

english, 2015

3

In vivo studies of the SERT-selective [18F]FPBM and VMAT2-selective [18F]AV-133 radiotracers in a rat model of Parkinson's disease

Julie L. Wang, Shunichi Oya, Ajit K. Parhi, Brian P. Lieberman, Karl Ploessl, Catherine Hou, Hank F. Kung

Journal:

Nuclear Medicine and Biology

Year:

2010

Language:

english

File:

PDF, 757 KB

english, 2010

4

Antibacterial activity of substituted dibenzo[a,g]quinolizin-7-ium derivatives

Parhi, Ajit, Lu, Songfeng, Kelley, Cody, Kaul, Malvika, Pilch, Daniel S., LaVoie, Edmond J.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 1.56 MB

english, 2012

5

Antibacterial activity of quinoxalines, quinazolines, and 1,5-naphthyridines

Parhi, Ajit K., Zhang, Yongzheng, Saionz, Kurt W., Pradhan, Padmanava, Kaul, Malvika, Trivedi, Kalkal, Pilch, Daniel S., LaVoie, Edmond J.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 799 KB

english, 2013

6

2-(2′-((Dimethylamino)methyl)-4′-(3-[18F]fluoropropoxy)-phenylthio)benzenamine for positron emission tomography imaging of serotonin transporters

Julie L. Wang, Ajit K. Parhi, Shunichi Oya, Brian Lieberman, Mei-Ping Kung, Hank F. Kung

Journal:

Nuclear Medicine and Biology

Year:

2008

Language:

english

File:

PDF, 567 KB

english, 2008

7

2-(2′-((Dimethylamino)methyl)-4′-(fluoroalkoxy)-phenylthio)benzenamine Derivatives as Serotonin Transporter Imaging Agents

Parhi, Ajit K., Wang, Julie L., Oya, Shunichi, Choi, Seok-Rye, Kung, Mei-Ping, Kung, Hank F.

Journal:

Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 193 KB

english, 2007

8

β-Lactam Antibiotics with a High Affinity for PBP2 Act Synergistically with the FtsZ-Targeting Agent TXA707 against Methicillin-Resistant Staphylococcus aureus

Ferrer-González, Edgar, Kaul, Malvika, Parhi, Ajit K., LaVoie, Edmond J., Pilch, Daniel S.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2017

Language:

english

File:

PDF, 2.53 MB

english, 2017

9

Combining the FtsZ-Targeting Prodrug TXA709 and the Cephalosporin Cefdinir Confers Synergy and Reduces the Frequency of Resistance in Methicillin-Resistant Staphylococcus aureus

Kaul, Malvika, Mark, Lilly, Parhi, Ajit K., LaVoie, Edmond J., Pilch, Daniel S.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2016

Language:

english

File:

PDF, 1.21 MB

english, 2016

10

A Weinreb Nitrile Oxide and Nitrone for Cycloaddition.

Ajit K. Parhi, Richard W. Franck

Journal:

Year:

2004

File:

PDF, 27 KB

2004

11

Synthesis of the mixed acetal segment of S-glyceroplasmalopsychosine

Ajit K. Parhi, David R. Mootoo, Richard W. Franck

Journal:

Year:

2008

Language:

english

File:

PDF, 364 KB

english, 2008

12

Substituted 1,6-diphenylnaphthalenes as FtsZ-targeting antibacterial agents

Zhang, Yongzheng, Giurleo, Daniel, Parhi, Ajit, Kaul, Malvika, Pilch, Daniel S., LaVoie, Edmond J.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 715 KB

english, 2013

13

A Bactericidal Guanidinomethyl Biaryl That Alters the Dynamics of Bacterial FtsZ Polymerization

Kaul, Malvika, Parhi, Ajit K., Zhang, Yongzheng, LaVoie, Edmond J., Tuske, Steve, Arnold, Eddy, Kerrigan, John E., Pilch, Daniel S.

Journal:

Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 2.15 MB

english, 2012

14

3-Hydroxyquinolin-2(1 H )-ones As Inhibitors of Influenza A Endonuclease

Sagong, Hye Yeon, Parhi, Ajit, Bauman, Joseph D., Patel, Disha, Vijayan, R. S. K., Das, Kalyan, Arnold, Eddy, LaVoie, Edmond J.

Journal:

ACS Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 2.12 MB

english, 2013

15

Structure-activity relationships of potentiators of the antibiotic activity of clarithromycin against Escherichia coli

Blankson, Gifty, Parhi, Ajit K., Kaul, Malvika, Pilch, Daniel S., LaVoie, Edmond J.

Journal:

European Journal of Medicinal Chemistry

Year:

2019

Language:

english

File:

PDF, 2.67 MB

english, 2019

16

TXA497 as a topical antibacterial agent: Comparative antistaphylococcal, skin deposition, and skin permeation studies with mupirocin

Dorrani, Mania, Kaul, Malvika, Parhi, Ajit, LaVoie, Edmond J., Pilch, Daniel S., Michniak-Kohn, Bozena

Journal:

International Journal of Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 353 KB

english, 2014

17

Structural Flexibility of an Inhibitor Overcomes Drug Resistance Mutations in Staphylococcus aureus FtsZ

Fujita, Junso, Maeda, Yoko, Mizohata, Eiichi, Inoue, Tsuyoshi, Kaul, Malvika, Parhi, Ajit K., LaVoie, Edmond J., Pilch, Daniel S., Matsumura, Hiroyoshi

Journal:

ACS Chemical Biology

Year:

2017

Language:

english

File:

PDF, 5.97 MB

english, 2017

18

Antibacterial activity of substituted 5-methylbenzo[c]phenanthridinium derivatives

Parhi, Ajit, Kelley, Cody, Kaul, Malvika, Pilch, Daniel S., LaVoie, Edmond J.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 1.44 MB

english, 2012

19

Enterococcal and streptococcal resistance to PC190723 and related compounds: Molecular insights from a FtsZ mutational analysis

Kaul, Malvika, Zhang, Yongzheng, Parhi, Ajit K., LaVoie, Edmond J., Tuske, Steve, Arnold, Eddy, Kerrigan, John E., Pilch, Daniel S.

Journal:

Year:

2013

Language:

english

File:

PDF, 1.67 MB

english, 2013

20

Inhibition of RND-type efflux pumps confers the FtsZ-directed prodrug TXY436 with activity against Gram-negative bacteria

Kaul, Malvika, Zhang, Yongzheng, Parhi, Ajit K., LaVoie, Edmond J., Pilch, Daniel S.

Journal:

Biochemical Pharmacology

Year:

2014

Language:

english

File:

PDF, 739 KB

english, 2014

21

Synthesis of fluorescent probes based on stilbenes and diphenylacetylenes targeting β-amyloid plaques

Ajit K. Parhi, Mei-Ping Kung, Karl Ploessl, Hank F. Kung

Journal:

Tetrahedron Letters

Year:

2008

Language:

english

File:

PDF, 143 KB

english, 2008

22

Medium effects on the reactions of coordination complexes: Base hydrolysisof(αβS)(p-hydroxybenzoato)(tetraethylenepentamine) cobalt(III) in iso-propanol–water, tert-butanol–water and dimethyl sulfoxide–water media

Ajit K. Parhi, Guru C. Pradhan

Journal:

Transition Metal Chemistry

Year:

1998

Language:

english

File:

PDF, 159 KB

english, 1998

23

Phenyl substituted 3-hydroxypyridin-2(1H)-ones: Inhibitors of influenza A endonuclease

Parhi, Ajit K., Xiang, Amy, Bauman, Joseph D., Patel, Disha, Vijayan, R.S.K., Das, Kalyan, Arnold, Eddy, LaVoie, Edmond J.

Journal:

Bioorganic & Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 919 KB

english, 2013

24

TXA709, an FtsZ-Targeting Benzamide Prodrug with Improved Pharmacokinetics and Enhanced In Vivo Efficacy against Methicillin-Resistant Staphylococcus aureus

Kaul, Malvika, Mark, Lilly, Zhang, Yongzheng, Parhi, Ajit K., Lyu, Yi Lisa, Pawlak, Joan, Saravolatz, Stephanie, Saravolatz, Louis D., Weinstein, Melvin P., LaVoie, Edmond J., Pilch, Daniel S.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2015

Language:

english

File:

PDF, 1.36 MB

english, 2015

25

A Weinreb Nitrile Oxide and Nitrone for Cycloaddition

Parhi, Ajit K., Franck, Richard W.

Journal:

Organic Letters

Year:

2004

Language:

english

File:

PDF, 54 KB

english, 2004

26

3-Phenyl substituted 6,7-dimethoxyisoquinoline derivatives as FtsZ-targeting antibacterial agents

Cody Kelley, Yongzheng Zhang, Ajit Parhi, Malvika Kaul, Daniel S. Pilch, Edmond J. LaVoie

Journal:

Bioorganic & Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 1.09 MB

english, 2012

27

Antimicrobial activity of various 4- and 5-substituted 1-phenylnaphthalenes

Kelley, Cody, Lu, Songfeng, Parhi, Ajit, Kaul, Malvika, Pilch, Daniel S., LaVoie, Edmond J.

Journal:

European Journal of Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 486 KB

english, 2013

28

Medium effect on the reactions of complexes: kinetics and mechanism of the base hydrolysis ofcis-[(salicylato)(amine)bis(ethylenediamine)cobalt(III)] compounds in methanol-water

Pradyumn K. Mohanty, Ajit K. Parhi, Guru C. Pradhan

Journal:

Transition Metal Chemistry

Year:

1996

Language:

english

File:

PDF, 419 KB

english, 1996

29

Pharmacokinetics and in vivo antistaphylococcal efficacy of TXY541, a 1-methylpiperidine-4-carboxamide prodrug of PC190723

Kaul, Malvika, Mark, Lilly, Zhang, Yongzheng, Parhi, Ajit K., LaVoie, Edmond J., Pilch, Daniel S.

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 901 KB

english, 2013

30

Advances in the structural studies of antibiotic potentiators against Escherichia coli

Blankson, Gifty A., Parhi, Ajit K., Kaul, Malvika, Pilch, Daniel S., LaVoie, Edmond J.

Journal:

Bioorganic & Medicinal Chemistry

Year:

2019

Language:

english

File:

PDF, 1.61 MB

english, 2019

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